Complete Guide to HiloWave Treatment|Effects · Duration · Side Effects · Filler Comparison · Price Guide

We’ve compiled a comprehensive guide to HiloWave, a dual hyaluronic acid skin booster that improves both natural volume and skin elasticity. This includes its effects, treatment intervals, potential side effects, price, and everything you need to know before your procedure.
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Nov 11, 2025
Complete Guide to HiloWave Treatment|Effects · Duration · Side Effects · Filler Comparison · Price Guide

HiloWave is a bio-stimulator type treatment that combines high-molecular and low-molecular hyaluronic acid. It is safer than traditional collagen boosters while delivering immediate volume improvement.


Here, we summarize the essential information you should know before undergoing HiloWave, including duration, recommended intervals, target areas (nasolabial folds, mid-face, sunken cheeks), side effects, price, and clinic selection.

Before and After HiloWave Treatment for Nasolabial Folds
Before and After Hilowave Treatment

Effects: Natural volume enhancement + improved skin elasticity


What is HiloWave Skin Booster?

HiloWave Product Photo
Hilowave Image

Though the name may be unfamiliar, HiloWave is a newly developed hyaluronic acid-based collagen stimulator treatment.

“Isn’t hyaluronic acid just a filler?”

Unlike traditional fillers, HiloWave works through a completely different mechanism.


HiloWave vs Filler

Traditional fillers are made by binding high-molecular hyaluronic acid with a cross-linking agent called BDDE. They are designed to fill depressed areas and maintain shape over a long period.

Recently, “natural volume” has become a trend, emphasizing treatments that stimulate your own collagen or fat cells to form volume naturally.

HiloWave features a dual HA structure combining high and low molecular weight HA, offering immediate volume and promoting long-term skin elasticity simultaneously.

HiloWave Low-Molecular-Weight Hyaluronic Acid Effect on Adipocyte Proliferation
Low-Molecular HA Effect on Adipocyte Proliferation

  • High-Molecular HA: Provides immediate volume, gradually broken down into low-molecular HA

  • Low-Molecular HA: Supplies moisture, stimulates collagen, enhances elasticity, and promotes fat cell proliferation

In short, HiloWave is a hybrid treatment that creates volume like a filler while also stimulating collagen like Juvélike Volume.

Before and After 2 cc HiloWave Treatment on Lateral and Anterior Cheeks
Before and After Hilowave Cheek Treatment


Differences from Traditional Collagen Stimulators

Traditional collagen boosters (PLA, PDO, CaHA, etc.) use synthetic polymers to stimulate cells to produce collagen.

  • Volume results may take a long time to appear

  • Overstimulation can lead to nodules

HiloWave, on the other hand:

  • High-molecular HA immediately creates volume

  • Low-molecular HA hydrates the skin while naturally promoting collagen production

This results in less cellular overstimulation, reducing the risk of nodules, and unlike permanent products, it can be dissolved with Hyalase.

Category

HiloWave

Traditional Collagen Booster

Onset of Effect

Immediate

Several months

Nodule Risk

Minimal

+ ~ ++


Duration and Treatment Interval

(1) Duration

Because HiloWave is less cross-linked than traditional fillers, its longevity is slightly shorter. However, volume is maintained to some extent over time through collagen production and fat cell proliferation.

  • Single treatment: 6–9 months

  • 3 treatments at 3-month intervals: Up to 18 months

HiloWave is more suitable for areas that need natural volume restoration rather than precise shaping:

  • Mid-face (front cheeks / cheekbones)

HiloWave Mid-Face Treatment Effect
Mid-Face Treatment Effect

  • Nasolabial folds

HiloWave Nasolabial Folds Treatment Effect
Nasolabial Folds Treatment Effect

  • Sunken cheeks

HiloWave Sunken Cheeks Treatment Effect
Sunken Cheeks Treatment Effect

Dosage: Typically 2cc per area; exact amount is determined during consultation with your doctor.


Side Effects

As a hyaluronic acid injection, HiloWave may carry minimal risks similar to fillers: vascular occlusion, foreign body sensation, or nodules, but the likelihood is significantly lower than with other treatments.

  • Small dual HA particles reduce risk of vascular blockage

  • Low incidence of foreign body reaction, nodules unlikely

  • Can be removed with Hyalase if desired

→ Suitable for those seeking safe volume enhancement


  • Those who want to improve sunken areas but find fillers too heavy

  • Concerned about side effects like nodules

  • Seeking natural and safe volume treatments

  • Targeting mid-face, nasolabial folds, or sunken cheeks

  • Looking for volume + skin elasticity + hydration improvement


Price Guide

  • HiloWave 2cc → 600,000 KRW

  • HiloWave 4cc → 1,000,000 KRW

  • HiloWave 6cc → 1,400,000 KRW

(※ Excluding VAT; additional discounts for 3-session treatments)


Exact costs will be provided during in-person consultation.


Clinic Selection Guide

Beyond price, the experience of the practitioner and clinic system is most important.

1️⃣ Doctor-led consultation
– Evaluate area, volume, and previous treatments

2️⃣ Varied treatment experience
– Choose clinics experienced with fillers, Juvélike, Sculptra, etc.

3️⃣ Post-treatment feedback system
– Ability to compare before-and-after photos and follow-up consultations


Frequently Asked Questions (FAQ)

Q. Can it be applied to the forehead or under-eye areas?
A. These areas require precise shape maintenance, so fillers are more suitable.

Q. Is the procedure painful?
A. Using a cannula, discomfort is minimal; slight tingling may be felt during numbing.

Q. Can I return to work immediately?
A. Unless bruising occurs, normal activities are possible; avoid alcohol, sauna, or intense exercise for one week.

Q. Can it be combined with other treatments?
A. Yes, but consultation with a doctor is recommended to confirm suitability.

Q. Will it spread or become lumpy?
A. Slight diffusion may occur, but it won’t cause unnatural shapes.


For those looking for immediate volume and long-term elasticity improvement, HiloWave is an excellent first choice.

This has been Dr. Kim Dohoon, ODE Clinic.


Author: Dr. Dohoon Kim, Chief Director of ODE Clinic
Specialty: Anti-aging (Lifting, Volumizing, etc.)

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