Complete Guide to HiloWave Treatment|Effects · Duration · Side Effects · Filler Comparison · Price Guide
HiloWave is a bio-stimulator type treatment that combines high-molecular and low-molecular hyaluronic acid. It is safer than traditional collagen boosters while delivering immediate volume improvement.
Here, we summarize the essential information you should know before undergoing HiloWave, including duration, recommended intervals, target areas (nasolabial folds, mid-face, sunken cheeks), side effects, price, and clinic selection.

Effects: Natural volume enhancement + improved skin elasticity
What is HiloWave Skin Booster?

Though the name may be unfamiliar, HiloWave is a newly developed hyaluronic acid-based collagen stimulator treatment.
“Isn’t hyaluronic acid just a filler?”
Unlike traditional fillers, HiloWave works through a completely different mechanism.
HiloWave vs Filler
Traditional fillers are made by binding high-molecular hyaluronic acid with a cross-linking agent called BDDE. They are designed to fill depressed areas and maintain shape over a long period.
Recently, “natural volume” has become a trend, emphasizing treatments that stimulate your own collagen or fat cells to form volume naturally.
HiloWave features a dual HA structure combining high and low molecular weight HA, offering immediate volume and promoting long-term skin elasticity simultaneously.

High-Molecular HA: Provides immediate volume, gradually broken down into low-molecular HA
Low-Molecular HA: Supplies moisture, stimulates collagen, enhances elasticity, and promotes fat cell proliferation
In short, HiloWave is a hybrid treatment that creates volume like a filler while also stimulating collagen like Juvélike Volume.

Differences from Traditional Collagen Stimulators
Traditional collagen boosters (PLA, PDO, CaHA, etc.) use synthetic polymers to stimulate cells to produce collagen.
Volume results may take a long time to appear
Overstimulation can lead to nodules
HiloWave, on the other hand:
High-molecular HA immediately creates volume
Low-molecular HA hydrates the skin while naturally promoting collagen production
This results in less cellular overstimulation, reducing the risk of nodules, and unlike permanent products, it can be dissolved with Hyalase.
Category | HiloWave | Traditional Collagen Booster |
|---|---|---|
Onset of Effect | Immediate | Several months |
Nodule Risk | Minimal | + ~ ++ |
Duration and Treatment Interval
(1) Duration
Because HiloWave is less cross-linked than traditional fillers, its longevity is slightly shorter. However, volume is maintained to some extent over time through collagen production and fat cell proliferation.
Single treatment: 6–9 months
3 treatments at 3-month intervals: Up to 18 months
(2) Recommended Areas
HiloWave is more suitable for areas that need natural volume restoration rather than precise shaping:
Mid-face (front cheeks / cheekbones)

Nasolabial folds

Sunken cheeks

Dosage: Typically 2cc per area; exact amount is determined during consultation with your doctor.
Side Effects
As a hyaluronic acid injection, HiloWave may carry minimal risks similar to fillers: vascular occlusion, foreign body sensation, or nodules, but the likelihood is significantly lower than with other treatments.
Small dual HA particles reduce risk of vascular blockage
Low incidence of foreign body reaction, nodules unlikely
Can be removed with Hyalase if desired
→ Suitable for those seeking safe volume enhancement
Recommended For
Those who want to improve sunken areas but find fillers too heavy
Concerned about side effects like nodules
Seeking natural and safe volume treatments
Targeting mid-face, nasolabial folds, or sunken cheeks
Looking for volume + skin elasticity + hydration improvement
Price Guide
HiloWave 2cc → 600,000 KRW
HiloWave 4cc → 1,000,000 KRW
HiloWave 6cc → 1,400,000 KRW
(※ Excluding VAT; additional discounts for 3-session treatments)
Exact costs will be provided during in-person consultation.
Clinic Selection Guide
Beyond price, the experience of the practitioner and clinic system is most important.
1️⃣ Doctor-led consultation
– Evaluate area, volume, and previous treatments
2️⃣ Varied treatment experience
– Choose clinics experienced with fillers, Juvélike, Sculptra, etc.
3️⃣ Post-treatment feedback system
– Ability to compare before-and-after photos and follow-up consultations
Frequently Asked Questions (FAQ)
Q. Can it be applied to the forehead or under-eye areas?
A. These areas require precise shape maintenance, so fillers are more suitable.
Q. Is the procedure painful?
A. Using a cannula, discomfort is minimal; slight tingling may be felt during numbing.
Q. Can I return to work immediately?
A. Unless bruising occurs, normal activities are possible; avoid alcohol, sauna, or intense exercise for one week.
Q. Can it be combined with other treatments?
A. Yes, but consultation with a doctor is recommended to confirm suitability.
Q. Will it spread or become lumpy?
A. Slight diffusion may occur, but it won’t cause unnatural shapes.
For those looking for immediate volume and long-term elasticity improvement, HiloWave is an excellent first choice.
This has been Dr. Kim Dohoon, ODE Clinic.
Author: Dr. Dohoon Kim, Chief Director of ODE Clinic
Specialty: Anti-aging (Lifting, Volumizing, etc.)